Which of the following medications is associated with an increased risk of rhabdomyolysis?

The correct medication associated with an increased risk of rhabdomyolysis is not antihistamines; rather, certain medications commonly prescribed for lowering cholesterol, such as statins, are more closely linked to this condition. Rhabdomyolysis involves the breakdown of muscle fibers that leads to the release of kidney-damaging proteins into the bloodstream, and it can occur due to several factors including the use of specific medications.

While antihistamines are generally not known to cause rhabdomyolysis, beta blockers, calcium channel blockers, and even aspirin have specific uses and side effects but do not present a direct risk for this condition in the way that certain statins do. It’s essential to be aware of the risk of rhabdomyolysis primarily associated with statins or muscle relaxants rather than the antihistamines listed.

In clinical practice, monitoring patients on medications with a known risk for muscle-related side effects, particularly statins, is crucial, especially when used in combination with other pharmacological agents that may exacerbate the risk. Understanding the pharmacology and potential adverse effects of these medications is vital for sports medicine practitioners to ensure safe management of athletes and active individuals.