Which medication class can induce acute narrow angle glaucoma?

The correct medication class that can induce acute narrow angle glaucoma is tricyclic antidepressants. These medications, which include amitriptyline and nortriptyline, can lead to anticholinergic effects. These effects can increase pupil dilation (mydriasis) and thus increase intraocular pressure in individuals predisposed to narrow-angle glaucoma.

In a person with anatomically narrow angles, the dilation of the pupil can obstruct the drainage of aqueous humor from the eye, leading to an acute rise in intraocular pressure, which can result in pain, blurred vision, and potentially permanent vision loss if not treated promptly.

Other classes such as beta-blockers, antihistamines, and SSRIs do not have the same association with acute narrow angle glaucoma. While beta-blockers are used to treat glaucoma by reducing aqueous humor production, antihistamines can sometimes cause pupil dilation but are not commonly implicated in causing acute narrow angle glaucoma. SSRIs do not have a significant link to this condition. Understanding the mechanism of action of these medications and their side effects is crucial in recognizing potential risks during patient treatment and management.