Which nerve innervates the first webspace of the foot?

The first webspace of the foot is primarily innervated by the deep peroneal nerve. This nerve provides sensory innervation to the skin between the first and second toes, which is considered the first webspace. The deep peroneal nerve arises from the common peroneal (fibular) nerve, which is responsible for supplying muscles involved in dorsiflexion of the foot and toes, as well as providing sensory input.

Anatomically, the deep peroneal nerve travels down the leg and runs alongside the anterior compartment, entering the foot to provide sensation. This relevant anatomical pathway underlines why the deep peroneal nerve is the correct response to this question.

The other nerves mentioned serve different regions. The superficial peroneal nerve primarily innervates the lateral compartment of the leg and provides sensation to the dorsum of the foot, but does not specifically address the first webspace. The tibial nerve innervates the muscles of the posterior compartment and provides sensation to the plantar aspect of the foot, while the sural nerve supplies sensory innervation to the lateral side of the foot and is not involved in the innervation of the first webspace.